Abstract
Autism spectrum disorder (ASD) is a range of complex neurodevelopment disorders, characterized by social impairments, communication difficulties, and restricted, repetitive, and stereotyped patterns of behavior. Its diagnosis is very difficult and consists of only clinical criteria. The aim of this study is to confirm autism disorder, among three children (2 girls and 1 boy), recruited in a social association of children in a precarious situation, located in Rabat, Morocco, and to evaluate some biological and neurobiological parameters among these children. The confirmation of autistic status is realized using Questionnaire (E2) and the evaluation of biological parameters (organic acids, urinary peptides, toxic metals and essential elements) is done in urine and hair of these children. Obtained children’s scores of E2 Questionnaire, is found in the favor of autism. Moreover, abnormal levels of urinary organic acids, urinary peptides, toxic and essential metals are observed.
Highlights
As defined by “The Diagnostic and Statistical Manual of Mental Disorders”, 4th edition (DSM IV) (2000), is a disorder of neural development characterized by impaired social interaction and verbal and non-verbal communication, and by restricted, repetitive or stereotyped behavior
In Morocco, very few studies are realized about autism [1] which cannot provide the prevalence in the Kingdom
Taken together with studies looking at families and twins, this suggests that autism has a genetic component
Summary
As defined by “The Diagnostic and Statistical Manual of Mental Disorders”, 4th edition (DSM IV) (2000), is a disorder of neural development characterized by impaired social interaction and verbal and non-verbal communication, and by restricted, repetitive or stereotyped behavior. In Morocco, very few studies are realized about autism [1] which cannot provide the prevalence in the Kingdom. The prevalence of this neurodevelopmental disorder is increasing; in the USA, from 1998 to 2007, the number of 6- to 21-year-old children receiving services for an ASD (autism spectrum disorders) in public special education programs increased from 54,064 to 258,305 [2]. In the recent CDC report, it is found that the overall estimated prevalence of ASD is one in 88 children during [3]. It is likely that a number of genes are involved. Other findings suggest that some neuroanatomical impairments in brain areas and/or brain chemistry changing could be involved in this neuropathology [5,6]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
