Abstract
Background: Corona virus causes severe pneumonia of idiopathic nature. The clinical manifestation ranges from mild to severe respiratory problems. Due presences of target receptors and the release of chemical mediators, it also affect other organs including the liver and kidney. Objective: The purpose of this study was to determine the effect of COVID-19 infection on hematological parameters, liver function and renal function. Methods: This multicenter case-control observational study was conducted at Lady reading hospital, Hayatabad medical complex and Khyber teaching hospital Peshawar. A total of 340 samples were processed including 170 COVID-19 patients and 170 control groups. Complete blood count, liver function tests and renal function tests were performed to determine the effect of COVID infection on these parameters. The data were statistically analyzed using SPSS version 22.0. Results: In complete blood count, the mean WBC count was 16632.34±7339.94 which was statistically significant with p value less than 0.05. In differential leukocyte count, the mean neutrophil values were 87.79±7.36 which was statistically significant (p=0.00). The mean value of ALT and ALP were 49.47±100.08, 114.43±64.71 respectively which were higher than the control group. Mean value of urea and creatinine were 70.58±41.89, 1.31±1.12 respectively and was statistically significant (p=0.00). Conclusion: it is concluded that COVID-19 infection affects hematological and biochemical parameters including ALT, ALP, urea and creatinine. Hence these manifestations can be used collectively as a diagnostic and prognostic biomarker. Keywords: Covid-19, liver function tests, Kidney Function Tests, blood cell count
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
