Abstract

This study was evaluated the protecting effect of rutin on the glycemic condition, lipid profile, instreptozotocin (STZ)-induced experimental diabetic in rats. With respect to an orally administrated rutinon serum glucose, the result is showing a significant decrease in glucose concentration when comparedto diabetic group, While, a significant increase in insulin concentration when compared to diabetic.Moreover, the results revealed that, an administration of streptozotocin (STZ) showing significantincrease in triacylglycerol, total cholesterol, LDL-c and VLDL-C concentration when compared withcontrol group, while, showing significant decrease in HDL-C concentration and serum AST and ALTactivity when compared to the control group. The data revealed also significant increase in serum LMDAconcentration. While, significant decrease in serum calcium concentration when compared to thecontrol group

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