Abstract
Introduction: Skull base (SB) reconstruction with a multilayer vascularized technique has proven to promote the best surgical outcomes, after endoscopic endonasal approaches (EEAs). The technique includes the use of a dural substitute as one of the layers, providing appropriate separation of the neurovascular tissue from the sinonasal cavity. Collagen matrix grafts are largely used in SB reconstructions, however the high costs of the material turn it inaccessible to many Neurosurgical centers in developing countries. Fascia lata is frequently used as an option, but its harvesting raises concerns regarding increasing of the total surgical time, morbidity of a second surgical site and local pain. Lyophilized biocellulose have been studied in several fields of Odontology and Medicine as human tissue substitute, including Neurosurgery. Studies showed its safety as dural substitute for convexity dural lesions, as a watertight, suture resistant and not brain adherent membrane.
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Schedule a callMore From: Journal of Neurological Surgery Part B: Skull Base
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