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Abstract
The development of biomedical science requires the creation of biological material collections that allow for the search and discovery of biomarkers for pathological conditions, the identification of new therapeutic targets, and the validation of these findings in samples from patients and healthy people. Over the past decades, the importance and need for biobanks have increased considerably. Large national and international biorepositories have replaced small collections of biological samples. The aim of this work is to provide a basic understanding of biobanks and an overview of how biobanks have become essential structures in modern biomedical research.
Highlights
Collections of biological material have been directly related to the development of biology as a science
The term “biobank” usually refers to a large, organized collection of well-characterized tissue samples, such as surgical biopsy specimens—freshly frozen or in paraffin sections, blood and serum samples, various types of cells and DNA—all carefully collected for research purposes and annotated [2]
The European Commission gives its own definition for biobank as an organized collection consisting of biological samples and related data that are of particular importance for fundamental science and the needs of personalized medicine [6]
Summary
Collections of biological material have been directly related to the development of biology as a science. Defines biobanks as an infrastructure for collecting human biological samples and related data, such as medical, family, social, and genetic [3]. Large international communities, such as the Organization for Economic Co-operation and Development (OECD), the International Community for Biological and Environmental Repositories (ISBER), the European Commission (EC) have their own definitions for the term “biobank”. The European Commission gives its own definition for biobank as an organized collection consisting of biological samples and related data that are of particular importance for fundamental science and the needs of personalized medicine [6]. This review purposed to cover the concept of modern biobank including aspects of ethical–legal issues, data safety and appropriate operating procedures specified for personalized medicine and bespoke treatment
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