Abstract
Purpose: To develop a simple, sensitive, accurate, precise and rapid UV spectrophotometric method for the determination of metformin in human urine. Methods: Extraction of metformin from urine samples was done by Dilute and shoot method in which urine was diluted up to 1:10 ratio to avoid interference of matrix. For estimation of Metformin hydrochloride, the solvent system employed was water. The metformin hydrochloride was scanned in range of 200nm to 400 nm and wavelength of detection (λdet) was found to be 234 nm. Result: The calibration curve was linear in the range of 1-17 μg/ml. the recovery and assay studies of metformin hydrochloride were within 93-94.85% indicating that the proposed method can be estimation of metformin hydrochloride
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
