Abstract

Bioanalytical HPLC method of Piper betle L. for quantifying phenolic compound, water-soluble vitamin, and essential oil in five different solvent extracts

Highlights

  • Regarding pharmaceutical development inviting utilization of organic compounds is broadly critical issue for human health properties, even more in animal welfare

  • Syahidah et al (2017) confirmed that the Piper betle L. has an abundant of flavonoids, tannins, and alkaloids where the methanolic assay was subjected under high-performance liquid chromatography with diode-array detection (HPLCDAD) machine

  • Rothwell et al (2012) reported syringic acid was present in cucumber 0.006, parsnip 0.011, and rosemary 0.015 mg/g, while our study addressed the vying numbers around eight times over comparing with rosemary number in both Piper betle L. contents of using polar solvents

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Summary

INTRODUCTION

Regarding pharmaceutical development inviting utilization of organic compounds is broadly critical issue for human health properties, even more in animal welfare. Commonly as polyphenols, had been considered as rife organic compound characteristic, ubiquitously in plants, fruits, and vegetables. These are secondary metabolites that contain simple phenolic molecules and benzene rings through shikimic and pentose phosphate pathway. We hypothesized that the natural organic compound of Piper betle L. and corroboration method for compelling its interaction were suspected necessary for further study. The aim was to identify and measure phenolic compound, water-soluble vitamin, and essential oil of Piper betle L. leaf as potential antioxidant, antimicrobial, and anticarcinogenic using different polarity of solvents by reverse phase HPLC-DAD

MATERIALS AND METHODS
Method validation
Findings
CONCLUSION
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