Abstract
A new and simple method for testing and classifying the bioadhesive behavior of polymeric microparticles with or without drugs is presented. The method is used to determine the adhesive forces between solid polymeric microparticles of diameter up to 200 μm in contact with natural mucosa or with a mucin gel. A theoretical analysis is presented in order to calculate the adhesive characteristics of spherical microparticles in contact with mucus.
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