Abstract
The Ti6Al4V alloy is usually employed as a biomaterial, however, when in use, exhibits a few drawbacks such as corrosion, caused by the release of aluminum and vanadium ions besides the bioinert behavior. Bioactive coatings offer a barrier effect and bioactivity, promoting biocompatibility and osseointegration processes. The present work aims to study the biocompatibility behavior of a bioglass-containing silane film deposited on a titanium alloy (Ti6Al4V) substrate. The effect of the surface roughness of the metallic substrate was also evaluated. Film/substrate systems were characterized as their morphological, chemical, physical, electrochemical behavior, and cell cytotoxicity and cell viability. The main results pointed out that silane films augment corrosion resistance of titanium alloy substrates. The biological results indicated a growth of osteoblast cells (MG-63), for all the test conditions. The bioglass film deposited on the ground substrate exhibits the highest cell density.
Highlights
The Ti6Al4V alloy is widely employed as a biomaterial in the orthopedic field
The results show that surface roughness directly influences the adhesion of the silane-based film to Ti-6Al-4V alloy
Coating the as-received titanium alloy with bioglass-free and bioglass-containing silane-based films provides the formation of a protective surface layer against corrosion in the simulated body fluid (SBF) medium
Summary
The Ti6Al4V alloy is widely employed as a biomaterial in the orthopedic field. It exhibits higher values of fracture and tensile strength and lower Young's modulus compared to other metallic materials (Chen & Thouas, 2015; Chiu et al, 2007; Fu et al, 2012). The harsh conditions of the physiological environment can result in metal corrosion. In this case, the corrosion mechanism is characterized by the occurrence of anodic and cathodic processes at metal/solution and oxide/solution interfaces (Mathew et al, 2012; Silva-Bermudez & Rodil, 2013). Corrosion and wear can cause inflammatory and allergenic reactions in the host body (Ahmed et al, 2016; Ibrahim et al, 2017; RodríguezCano et al, 2013)
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