Bioactivity, chemical profiling, and validation of Moringa oleifera cultivated in Suncheon (KR)

Abstract

Moringa oleifera is a vegetable rich in vitamins, minerals, and other nutrients that can be used medicinally to enhance human health. This study described how the antioxidative properties of several organs of M. oleifera were used to optimise extraction conditions through their antioxidative capacity. In addition, an analytical approach applying seven marker chemicals was developed and used to construct the chemical profile while simultaneously ascertaining the primary components and their contents in the leaf extract. Of those, the content of quercetin 3-O-malonylglucoside (5) was the greatest, at 12.50 mg/g, followed by neochlorogenic acid (1) at 5.67 mg/g. In a study using molecular docking to target antioxidation, the main constituents of the leaf extract provided some evidence. This was the first study to analyse M. oleifera grown in Suncheon and provide an effective analytical tool to control and verify the quality of this plant species by using standards.