Abstract

Safflower flowers (Carthamus tinctorius) contain many natural substances with a wide range of economic uses. The most famous dye isolated from flower petals is hydroxysafflor A (HSYA), which has antibacterial, anti-inflammatory, and antioxidant properties. This review is aimed at updating the state of knowledge about their applicability in oncology, pulmonology, cardiology, gynecology, dermatology, gastrology, immunology, and suitability in the treatment of obesity and diabetes and its consequences with information published mainly in 2018-2020. They were also effective in treating obesity and diabetes and its consequences. The issues related to the possibilities of using HSYA in the production of health-promoting food were also analyzed.

Highlights

  • The demand for natural compounds used in the key branches of economy is increasing in connection with the growing awareness of consumers

  • Saffron is known for its rich chemical composition: simple and complex sugars, amino acids, proteins, lipids, cellulose, mineral compounds, and vitamins, including thiamine and riboflavin, low amounts of α-carotene and β-carotene, zeaxantin, and lycopene

  • In China, hydroxysafflor yellow A (HSYA) is recommended for the treatment of angina pectoris [75] and other circulatory disorders [76]

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Summary

Introduction

The demand for natural compounds used in the key branches of economy is increasing in connection with the growing awareness of consumers. Producers are forced to follow economic considerations and use cheaper equivalents of certain ingredients. For this reason, safflower (Carthamus tinctorius), treated as a low-cost replacement for saffron crocus (Crocus sativus L.) and as a rich source of bioactive substances, has been applied in numerous branches of economy. The content and bioactivity of several glycosides in flowers (safranal, picrocrocin, crocetin, and crocins) are an indicator of the attractiveness of this plant [1,2,3,4,5,6,7] These glycosides have not yet been found in safflower flowers

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