Abstract
This study compared the total flavonoid content of Glycyrrhiza glabra L. leaf and root extracts. Results suggested that the total flavonoid content in the leaf extract was obviously higher than that in the root extract. Pinocembrin, the main compound in the leaf extract after purification by column chromatography, showed good antioxidant activity and nitrite scavenging capacity, but moderate inhibitory effect on mushroom tyrosinase. Liquiritin was the main compound in root extract and possessed strong inhibitory effect on mushroom tyrosinase. Both compounds exhibited significant protection effect on H2O2-injured PC12 cells at a low concentration. These results indicate that Glycyrrhiza glabra L. leaf is potential as an important raw material for functional food.
Highlights
Licorice, which belongs to the legume family, is widely distributed in various areas of the world.Licorice distributed in Northwest ChinaMolecules 2014, 19 performs the best quality [1]
In order to make a full use of Glycyrrhiza glabra L., we comparatively evaluated the chemical profile, antioxidant activity, inhibitory effect on mushroom tyrosinase and nitrite scavenging capacity of Glycyrrhiza glabra L. leaf and root extracts, separated and identified the main compound in the leaf extract as well
The sodium borohydride/chloranil-based assay was chosen for measuring Total Flavonoid Content (TFC) in the leaf and root extracts
Summary
Licorice, which belongs to the legume family, is widely distributed in various areas of the world. Licorice is always considered as the root and root-like stem in Traditional Chinese Medicine [2]. There was little information about the chemical profile and biological activity of licorice leaf. In order to make a full use of Glycyrrhiza glabra L., we comparatively evaluated the chemical profile (the total flavonoid content), antioxidant activity (oxygen radical absorbance capacity), inhibitory effect on mushroom tyrosinase and nitrite scavenging capacity of Glycyrrhiza glabra L. leaf and root extracts, separated and identified the main compound in the leaf extract as well. It is the first time to make a comparison of the chemical profiles and bioactivities between Glycyrrhiza glabra L. leaf and root extracts, which could be the theory guidance for making a full use of Glycyrrhiza glabra L
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
