Abstract
Bioactive Peptides in Cancer: Therapeutic Use and Delivery Strategies
Highlights
One of the most interesting peptides of natural origin is Urotensin-II (U-II) originally isolated from the goby urophysis and subsequently identified in humans
It was recently reported by several groups a potential role of U-II and its receptor in the regulation of cancer biology
Other peptides with anticancer properties are peptide hormones acting on the pituitary axis in the treatment of endocrinological cancers such as breast and prostate cancer and peptides acting on neuroendocrine receptors such as somatostatin and BN/GRP
Summary
One of the most interesting peptides of natural origin is Urotensin-II (U-II) originally isolated from the goby urophysis and subsequently identified in humans. Several peptides have been isolated from natural products and/or physiological sources and several of them have biological activity on cancer cells. This special issue addresses the role of these natural peptides and of their synthetic derivatives in cancer therapy, alone or in combination with other anticancer agents.
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