Abstract

Non-communicable diseases (NCD) are the leading cause of death and disability worldwide. The four main leading causes of NCD are cardiovascular diseases, cancers, respiratory diseases and diabetes. Recognizing the devastating impact of NCD, novel prevention and treatment strategies are extensively sought. Marine organisms are considered as an important source of bioactive peptides that can exert biological functions to prevent and treatment of NCD. Recent pharmacological investigations reported cardio protective, anticancer, antioxidative, anti-diabetic, and anti-obesity effects of marine-derived bioactive peptides. Moreover, there is available evidence supporting the utilization of marine organisms and its bioactive peptides to alleviate NCD. Marine-derived bioactive peptides are alternative sources for synthetic ingredients that can contribute to a consumer’s well-being, as a part of nutraceuticals and functional foods. This contribution focus on the bioactive peptides derived from marine organisms and elaborates its possible prevention and therapeutic roles in NCD.

Highlights

  • Non-communicable diseases (NCD), sometimes referred to as chronic diseases, are the leading cause of death and disability globally [1,2]

  • NCD are not passed from person to person, and these diseases are of long duration and slow progression

  • Bioavailability should be taken into account when developing food and beverages products containing marine-derived bioactive peptides for the prevention and treatment of NCD

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Summary

Introduction

Non-communicable diseases (NCD), sometimes referred to as chronic diseases, are the leading cause of death and disability globally [1,2]. Of the 56 million global deaths in 2012, 68% or 38 million were attributed to NCD and projected to rise further worldwide. It highlights and compiles the most relevant studies on the structural diversity of peptides found in found in these marine organisms and outlines their potential as candidate raw materials for the these marine organisms and outlines their potential as candidate raw materials for the generation of generation of bioactive peptides Their possible biological role with potential utilization as bioactive peptides.

Marine-Derived Cardio Protective Peptides
Marine-Derived Renin Inhibitory Peptides
Marine-Derived ACE Inhibitory Peptides
Marine-Derived Anti-Cancer Peptides
Anti-Cancer Peptides Derived from Sponges
Anti-Cancer Peptides Derived from Fish
Anti-Cancer Peptides Derived from Urochordata
Anti-Cancer Peptides Derived from Mollusks
Anti-Cancer Peptides Derived from Cyanobacteria
Marine-Derived Antioxidant Peptides
Future Perspectives of Marine-Derived Bioactive Peptides
Findings
Conclusions
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