Abstract
Today, nanomedicine seeks to develop new polymer composites to overcome current problems in diagnosing and treating common diseases, especially cancer. To achieve this goal, research on polymer composites has expanded so that, in recent years, interdisciplinary collaborations between scientists have been expanding day by day. The synthesis and applications of bioactive GQD-based polymer composites have been investigated in medicine and biomedicine. Bioactive GQD-based polymer composites have a special role as drug delivery carriers. Bioactive GQDs are one of the newcomers to the list of carbon-based nanomaterials. In addition, the antibacterial and anti-diabetic potentials of bioactive GQDs are already known. Due to their highly specific surface properties, π-π aggregation, and hydrophobic interactions, bioactive GQD-based polymer composites have a high drug loading capacity, and, in case of proper correction, can be used as an excellent option for the release of anticancer drugs, gene carriers, biosensors, bioimaging, antibacterial applications, cell culture, and tissue engineering. In this paper, we summarize recent advances in using bioactive GQD-based polymer composites in drug delivery, gene delivery, thermal therapy, thermodynamic therapy, bioimaging, tissue engineering, bioactive GQD synthesis, and GQD green resuscitation, in addition to examining GQD-based polymer composites.
Highlights
Bioactive materials play an increasingly important role in the biomaterials industry and have wide applications in nanomedicine, drug delivery systems, and biosensors
Graphene and bioactive GQD based polymer composites have been widely used in medicine for drug delivery, cancer treatment, tissue engineering, phototherapy, and stem cell and biosensor separation [58,59]
This study aimed to present advances in bioactive graphene quantum dot-based polymer composites, focusing on advances in bioactive GQD-based synthesis methods and highlighting future work areas in this field
Summary
Bioactive materials play an increasingly important role in the biomaterials industry and have wide applications in nanomedicine, drug delivery systems, and biosensors. The potential application of graphene sheets [34–36] as fillers is possible due to their outstanding optical, electrical, and mechanical properties in the context of synthesizing new nanocomposites based on polymers [37–40]. Information on GQD-polymer composites, including the small size of GQD particles, their atomic rough surfaces, and the dispersibility in polymers have been obtained through simultaneous studies of their mechanical properties and thermal conductivity [51]. Graphene and bioactive GQD based polymer composites have been widely used in medicine for drug delivery, cancer treatment, tissue engineering, phototherapy, and stem cell and biosensor separation [58,59]. This study aimed to present advances in bioactive graphene quantum dot-based polymer composites, focusing on advances in bioactive GQD-based synthesis methods and highlighting future work areas in this field. The applications of bioactive GQD-based polymer composites, including drug delivery, gene delivery, heat treatment, thermodynamic therapy, bioimaging, and tissue engineering, are discussed. Dual-function precursors have not yet been developed to obtain bioactive CDs
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