Abstract
Lathyrus species are economically important as food, fodder, and folk medicine. The antioxidant properties (radical scavenging effectiveness, reducing power potentials, metal chelating ability, phosphomolydenum capacity) phytochemical characterization (phenolic composition), and enzyme inhibition abilities of the water and ethyl acetate extracts of Lathyrus czeczottianus (LC) were tested. The phenolic ingradients of LC extracts were evaluated by HPLC-DAD (High-performance liquid chromatography with diode array detector). Chlorogenic acid, epicatechin, and benzoic acid were found as main phenolic compounds in both extracts. Generally, the water extract revealed strong antioxidant potential. The antioxidant effectiveness could be explained by high total phenolic level in the extract. Regarding enzyme inhibitory results, the ethyl acetate extract indicated good inhibitory activities on cholinesterase (for AChE: Acetylccholinesterase 1.15 mg galathamine equivalents (GALAE/g extract) and for BChE: Butyrylcholinesterase 0.19 mg GALAE/g extrac), tyrosinase (54.48 mg kojic acid equivalents (KAE/g)), and α-amylase (0.34 mmol acarbose equivalents (ACEs/g)), while the water extract had just good inhibition on α-glucosidase (6.49 mmol ACEs/g). In conclusion, L. czeczottianus could be good valuable of bioactive molecules for pharmaceuticals, food and agriculture, and nutraceutical applications.
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