Abstract

Aging is a complicated biological process in which functional and structural alterations in a living organism take place over time. Reactive oxygen species is one of the main factors responsible for aging and is associated with several chronic pathologies. The relationship between aging and diet is quite interesting and has attained worldwide attention. Healthy food, in addition to dietary antioxidants, are required to delay the process of aging and improve the quality of life. Many healthy foods such as fruits are a good source of dietary nutrients and natural bioactive compounds which have antioxidant properties and are involved in preventing aging and other age-related disorders. Health benefits linked with healthy consumption of fruit have drawn increased interest. A significant number of studies have documented the advantages of fruit intake, as it suppresses free-radical development that further reduces the oxidative stress created in the body and protects against several types of diseases such as cancer, type 2 diabetes, inflammatory disorders, and other cardiovascular diseases that ultimately prevent aging. In addition, fruits have numerous other properties like anti-inflammatory, anti-cancerous, anti-diabetic, neuroprotective, and have health-promoting effects. Mechanisms of various bioactive compounds that aids in preventing various diseases and increases longevity are also described. This manuscript provides a summary of various bioactive components present in fruits along with their health-promoting and antiaging properties.

Highlights

  • Aging is a slow process of physiological deterioration that each living organism experiences with time

  • The findings indicated that certain threat factors for cardiovascular disease (CVD) in subjects with diabetes were improved by the intake of strawberries over a short period of time [226]

  • As there is an increase in the prevalence of oxidative stress-mediated aging and other associated chronic pathologies, there is a need to improve the body’s defense mechanism with the least side effects

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Summary

Introduction

Aging is a slow process of physiological deterioration that each living organism experiences with time. An imbalance between overproduction or accretion of free radicals in the body and the potential of a biological system to detoxify the reactive substances results in oxidative stress, which is the leading factor in the development of several degenerative and age-linked chronic disorders [7,8]. Several research findings have reported that healthy fruit intake is related to a lower prevalence of chronic diseases [15,16,17,18,19] Various fruits and their derivatives are well-known to hold an elevated level of naturally occurring polyphenolic compounds [18,20,21,22]. Polyphenols are the plant secondary metabolites with antioxidant properties that function as free radical inhibitors and play a vital part in reducing oxidative stress that prevents aging and their associated diseases [23,24]. The main purpose of this manuscript is to develop an outline about various nutraceuticals and bioactive compounds present in fruits, and their anti-aging, and other health-promoting properties that increase life expectancy in humans

Free Radicals and Aging
Vitamins
Bioactive Compounds
Phenolic Acids
Flavonoids
Tannins
Stilbenes
An Insight into Pharmacological and Biological Benefits of Fruits
Anti-Aging Effects
Results
Antioxidant Effects
Anti-Inflammatory Effects
Anticancer Effects
Neuroprotective Effects
Anti-Diabetic Effects
Conclusions
Full Text
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