Bioactive Compounds Investigation From Methanol Bark Extract of Pterocarpus marsupium Using GC-MS Analysis

Abstract

Introduction: Medicinal plants still represent untapped sources of novel compounds with potential therapeutic effects for mitigating human maladies.Pterocarpus marsupium, commonly known as Bijasal, is a well-known drug in ayurvedic system of medicine. Materials and methods: The dried bark powder of P.marsupium was extracted by Soxhlet with methanol and analyzed by gas chromatography, while the mass spectra data of the compounds found in the extract was matched with the data available at National Institute of Standards and Technology (NIST) library. Results: The results of the GC-MS analysis provide different peaksdetermining the presence of 10 major phytocomponents, that are 1-Penten-3-one,1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-; Geranyl isovalerate; 2-Pentadecanone,6, 10, 14-trimethyl;Cyclopropaneoctanal, 2-octyl-; Octadecanoic acid;10-Octadecanoic acid, methyl ester; Heptadecanoic acid, 16-methyl,-methyl ester; Phytol; 4,8,12,16-Tetramethyl heptadecan-4-olide; Dasycarpidan-1-methanol, acetate with different therapeutic activities. Conclusion: The presence of these bioactive compounds justifies that the Pterocarpus marsupiumcan offer a base for using this compound as herbal alternative for the synthesis and development of new drug to treat various infectious diseases. However, isolation of individual phytochemical constituents might be useful to formulate a new novel drug.