Bioactive Compounds and Bioactivities of Centella asiatica (L.) Urban Prepared by Different Drying Methods and Conditions

Abstract

Centella asiatica (L.) Urban has attracted significant research and commercial interest due to its many health-promoting bioactive compounds, especially phenolic compounds and triterpene saponins, which possess several functional capacities, including antioxidant activity and antimicrobial activity. Prior to its use, however, C. asiatica usually needs to be dried to extend its storage life and to prepare the material for subsequent pharmaceutical processing. The present study investigated the effects of selected drying methods and temperature on the drying characteristics, phenolic compounds, triterpene saponins, antioxidant activity, and antimicrobial activity of dried C. asiatica. Hot-air drying (HAD), combined infrared–hot air drying (IR-HAD), and low-pressure superheated steam drying (LPSSD) were carried out at various temperatures (50, 60, 70°C). The results showed that higher drying temperatures led to higher drying rates but to lower levels of total phenolic compounds, total triterpene saponins, antioxidant activity, and antimicrobial activity. At the same drying temperature, IR-HAD resulted in the highest drying rates; this was followed by LPSSD and HAD in a descending order. Nevertheless, LPSSD resulted in the highest levels of the tested bioactive compounds, antioxidant activity, as well as antimicrobial activity. LPSSD at 50°C yielded dried C. asiatica of the best overall quality.