Abstract
AbstractBone tissue, unlike most tissues, has the ability of complete regeneration if provided with precise materials and bioactive agents. Regeneration course, however, is a highly complex process engrossing significant problems when failed. Bone grafts are indispensable in orthopedic, craniofacial and periodontal surgeries to fill the dead space, to provide support for the newly forming tissues, and to augment regeneration/treatment via its bioactive components. These multifunctional scaffolds can be categorized according to the bioactive agent they supply or by their carrier material composition. As one group of bioactive agents, growth factors, cytokines, chemokines, statins, etc. are mainly considered for regeneration of large bone defects as well as for defects in hosts with impaired regeneration capacity. The second bioactive group, antibiotics, is mostly used in clinic for infectious bone disease treatment throughout the regeneration period. They are, however, still being studied for development of more efficient forms. This chapter summarizes the most recent studies and trends in scaffolds for bone regeneration with controlled release of bioactive agents.KeywordsBone regenerationBone scaffoldsAntibioticsGrowth factorsStatins
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
