Abstract
4-Ipomeanol (IPO1; 1-(3-Furyl)-4-hydroxy-1-pentanone) is a furanoterpenoid toxin produced by sweet potatoes (Ipomoea batatas) in response to infection by the mold Fusariam solani (Doster et al., 1978). Cattle that ingest infected sweet potatoes can develop interstitial pneumonia that is characterized by pulmonary edema and emphysema. Moldy sweet potatoes have been linked to the death of livestock since 1952 (Monlux et al., 1953), including recent cases in Wisconsin where 200 steer died (Spoto, 2011) and England, where six cows died in what is believed to be the first case of IPO toxicity in the UK (Steckel and Rhodes, 2007). IPO is lethal to cattle in doses as low as 7.5 mg/kg which can be achieved by ingesting as little as 6 kg of spoiled sweet potatoes (Doster et al., 1978).
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