Abstract
A model for the complete system of bioaccumulation, transport, and biotransformation of polyphenolic compounds (flavonols) that includes hemoglobin-containing red blood cells and serum albumin was proposed. The distribution of flavonols between the erythrocyte fraction and albumin was studied. Hemoglobin was shown to play a role in the biotransformation of flavonols. The formation of several intermediate and final products of pseudoperoxidase oxidation of flavonols catalyzed by methemoglobin was established by UV spectrophotometry and RP-HPLC.
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