Bioaccessibility of lead in Dittrichia viscosa plants and risk assessment of human exposure around a fertilizer industry in Lebanon

Abstract

Total and bioaccessible lead (Pb) concentrations in Dittrichia viscosa and soil samples were considered for estimating the potential health risk, related to both plant intake and accidental soil ingestion by adult and child consumers, near a Lebanese fertilizer plant. A total of 27 plant samples, from 9 uncultivated sites situated around the plant, were analyzed in order to assess the total and bioaccessible Pb content. Physiologically based extraction test (PBET) was used to estimate oral bioaccessibility of Pb in edible plant parts. Washed and unwashed leaves were compared in order to show the importance of good consumer practice on Pb intake. Extracted Pb in the intestinal medium accounted for 24 up to 87% of Pb extracted in the gastric medium. The total hazard quotient (HQtot) and the total bioaccessible hazard quotient (BHQ), related to both plants' intake and soil ingestion, for two maximalist child and adult scenarios, were calculated in order to estimate human health risk assessment. HQtot estimations considering the total concentration of Pb in soil and plant suggest that this metal is a contributor in elevating health risks problems on local plants’ consumers, especially children inhabitants. However, the integration of bioaccessible concentrations of Pb in risk estimations reduces remarkably the potential risk.