Bio-Fabrication and Efficiency Analysis of Annona Muricata Extract Coated on Bamboo Fiber for Wound Healing Application

Abstract

ABSTRACT This study focusses on the bio-fabrication of leaf extracts of Annona muricata dyed bamboo woven fabric and its application in wound healing. Annona muricata was exposed to ultrasonic-assisted extraction (UAE) with acetone for fabric finishing. Bioactivity is characterized and employed in textile fabric coating to evaluate the efficacy of its antibacterial and wound healing characteristics. The treated fabric was then tested for antibacterial activity using gram-positive and gram-negative bacteria, aroma, color intensity, olfaction, and invivo wound healing. The invivo test was carried out in wistar rats for 21 days for 50%, 75%, and 100%. According to the results of the analysis, the extract is a good antibacterial agent against gram-positive bacteria (Bacillus subtilus) and gram-negative bacteria (Pseudomonas sp.), which aids in the prevention of bacteria and other germs from sticking to the injured area since the leaf extracts have high antibacterial properties. The wound healing impact of the plant extract coated with bamboo fabric on in vivo wound models in rats (Wistar albino rats) demonstrated a significant increase in wound closure, showing the efficacy of the coated fabric.