Abstract
A 3D-printable composite material consisting of gold nanoparticles embedded within a poly-2-hydroxyethylmethacrylate matrix, that serves dual functions as both host framework scaffold for pre-osteoblasts, as well as a non-invasive plasmonic biosensor for cellular metabolites, is presented in article number 2001040 by Ralph G. Nuzzo and co-workers. The 3D printing ink is particle-free and the gold nanoparticles are generated in the 3D-printed scaffolds via a postprint chemical reduction method. Pre-osteoblast cells are successfully grown and differentiated into mature osteoblasts over the 3D printed scaffolds. Cellular metabolites are detected using surface-enhanced Raman spectroscopy during different stages of cell growth and differentiation. Common cellular, as well as some free amino acids, are detected using SERS demonstrating the ability of the composite material to function as a biologically compliant plasmonic biosensor in cell culture applications.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
