Year-end Sale % OFF 
Abstract
The kinetics of binucleate cell formation and their relationship to the recovery of primary cell damage were investigated using mouse mammary carcinoma cells (FM3A) grown in suspension. The following results were obtained: (i) the percentage of binucleate cells increased with the dose to a maximum on the second or third day postirradiation when the rate of proliferation was at a minimum; (ii) the percentage of binucleate cells was smaller following two split doses (2 × 500 rad, at a 4-hr interval) than following a single (1000-rad) dose; and (iii) the percentage of binucleate cells decreased with treatment of the cells with Hanks' balanced salt solution (HBSS) immediately postirradiation (1000 rad). These results suggest that radiation-induced binucleate cell formation plays an important role in reproductive cell death.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
