Binding sites of monoclonal anti-carbohydrate antibodies.

Abstract

This chapter presents an overview of monoclonal antibodies (mAbs) directed to carbohydrates in mammalian systems with well-characterized specificities, together with some of the information obtained from their use. Because of the rapidly increasing number of this kind of reagent not all available mAbs are included. Naturally occurring mAbs and embryological markers and their suspected immunogenicity have been extensively reviewed by Hakomori (1984) and Feizi (1985).