Abstract
3,5,6,11-Tetrahydro-2 H-imidazo[1′,2′:1,2]pyrido[3,4- b]indole ( 10) might be viewed as a fusion structure of two classes of I 2 imidazoline receptor ligands: 2-(2-benzofuranyl)-2-imidazolines and β-carbolines. Its high affinity ( K i=7.3 nM) provides insight to how the two classes of agents might bind relative to one another at I 2 receptors.
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