Abstract
Abstract—The affinities of 5‐hydroxy‐[3H]tryptamine (5‐HT) for cerebroside sulfate, 1‐phosphatidylinositol, 1‐phosphatidylinositol 4‐phosphate, 1‐phosphatidylinositol 4,5‐bisphosphate, phosphatidic acid, and phosphatidyl serine were determined in an aqueous medium. They were observed to be, in general, much lower than and poorly correlated with the values previously reported by Johnsonet al (1977a), measured in isobutanol. This suggested that these lipids probably are not 5‐HT receptors and that drug affinities measured in organic media must be evaluated with caution.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.