Abstract
A new bimetallic Ru(II) complex bridged by (Z)-1-(4-fluorobenzyl)-3-((4-fluorophenyl)(3H-pyrrolo[3,4-f]isoquinolin-3-ylidene)methyl)-2H-pyrrolo[3,4-f]isoquinoline has been synthesized and characterized by electronic spectroscopy, 1HNMR, HRMS, and elemental analysis. Binding studies with calf thymus DNA (ctDNA) show binding constants as high as 105M−1 indicating a strong interaction of the complex with DNA. When aqueous solutions of the complex and plasmid DNA are irradiated with low energy light for brief periods of time, complete photocleavage of the DNA is observed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
