Abstract
The detection of uric acid (UA) is important not only in biomedicine and neurochemistry but also in disease diagnosis and pathology research. Herein, a family of bimetallic-organic frameworks, MIL-125(Ti–Cr)-xNH2 (x = 0 %, 25 %, 50 %, 75 %, and 100 %), was successfully prepared. MIL-125(Ti–Cr)-xNH2 series were used as electrochemical sensors for the detection of UA, and MIL-125(Ti–Cr)–0%NH2 exhibited the most promising behavior with 70 % carbon black doping in 0.1 M PBS (pH = 6.0). In addition, the as-prepared MIL-125(Ti–Cr)–0%NH2/GCE exhibited good stability and anti-interference behavior, which offered a promising platform for future utilization in real sample analysis.
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