Abstract

The kinetics of biliary excretion of mercury applied as phenyl mercury (203) chloride (PMC) or methyl mercury (203) chloride (MMC) were studied in rats during the first 24 hours after intravenous administration. The content of total mercury in the bile, plasma, liver, kidneys, gastrointestinal tract, urine, and feces was determined. The enterohepatic circulation of mercury after administration of PMC in rats was compared with that after administration of MMC or inorganic mercury. The differences found in both the kinetics and the distribution of PMC, MMC, and inorganic mercury in rats were discussed.

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