Abstract
An in vitro model was developed to measure bile flow at varied pressures through several commonly used transhepatic drainage catheters. As expected, larger catheters conduct more bile flow at a given pressure. All catheters studied conduct adequate amounts of bile at normal physiologic pressure gradients. The clinical observation that large catheters (10-12 French) are necessary for adequate antegrade drainage in some patients must be explained by an abnormal bile viscosity, increased duodenal pressures, or reduced biliary secretory pressure.
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