Bildgebende Diagnostik des invasiv lobulären Mammakarzinoms

Abstract

Early diagnosis of invasive lobular breast carcinoma by physical examination and mammography is often difficult. It is thus often diagnosed only at an advanced tumor stage. Sonography of the breast can increase the sensitivity for diagnosis of invasive lobular breast cancer, but this modality has its limitations even when performed by experienced investigators. The combination of mammography and sonography also has limitations, particularly with regard to the staging of the invasive lobular cancer, as tumor dimensions are often underestimated and multifocality or multicentricity often not recognized. At present, MR mammography is the most sensitive modality for the diagnosis and staging of invasive lobular breast cancer. It has therefore been recommended for local staging of invasive lobular carcinoma in the updated stage 3 guidelines for the early detection of breast cancer in Germany 2008.