Abstract

The pH-dependent structure and stability of dihexadecyl phosphate (DHP) bilayer dispersions are determined by using fluorescent and spin probes. The hydrocarbon core region is probed by diphenylhexatriene (DPH) while the polar head/water interface is probed by either trans-parinaric acid (TPA) or an iminoxyl derivatives of stearamide spin-label (SSL). At 5 mM NaCl, the fluorescence depolarization (FP) of DPH or TPA goes through a maximum as pH increases for vesicles prepared and maintained at a given pH value

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