Abstract

We report a case of 48-year old woman who presented with dementia, progressive mental decline, personality change, paresis of the right lower extremity, and gait ataxia. Magnetic resonance imaging (MRI) T1-weighted image revealed bilateral thalamic swelling with homogenous low signal intensity and mild contrast enhancement with gadolinium. The T2- weighted image showed high intensity lesions in the bilateral thalamus, septum pellucidum and fornix. A CT-guided stereotactic biopsy of the lesion revealed fibrillary astrocytoma grade III as per WHO classification. Bilateral thalamic gliomas are very rare tumours and when present may resemble other benign diseases having similar clinical presentations DOI: http://dx.doi.org/10.3126/jonmc.v3i1.10059 Journal of Nobel Medical College Vol.3(1) 2014; 71-73

Highlights

  • We report a case of 48-year old woman who presented with dementia, progressive mental decline, personality change, paresis of the right lower extremity, and gait ataxia

  • A 48-year-old woman was admitted to our department with complaints of progressive memory loss, personality changes, dizziness, ataxia and weakness in her extremities for five months

  • A CT-guided stereotactic biopsy was performed with consultation of neurosurgeons

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Summary

Introduction

We report a case of 48-year old woman who presented with dementia, progressive mental decline, personality change, paresis of the right lower extremity, and gait ataxia. Primary thalamic tumors are rare and bilateral thalamic gliomas are even more rare [2]. Thalamic astrocytomas are not diagnosed as their clinical presentation are often nonspecific and conventional neuroimaging findings are not typical for the tumors, and can be mistaken for other diseases [3,4,5].

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