Abstract
Purpose: The purpose of this study is to assess the relationship between Clomifene citrate and retinal detachment in particular. Methods: a 42-year-old woman has developed bilateral retinal detachment after three courses of clomiphene citrate. A literature research for bilateral retinal detachment does not include this severe ophthalmologic complication. Conclusion: This is the first reported case of bilateral retinal detachment after treatment with clomiphene citrate. The caution is warranted in treating infertility patients with CC, and patient should be well informed of this side effect before prescribing this therapy by gynecologist.
Highlights
Retinal detachment, as well as central retinal artery occlusion, endophthalmitis, chemical burn is one of the most time-critically ocular emergencies that have been associated with various ocular and systemic conditions [1]
The caution is warranted in treating infertility patients with CC, and patient should be well informed of this side effect before prescribing this therapy by gynecologist
Retinal detachment is a rare condition in fertility patients
Summary
As well as central retinal artery occlusion, endophthalmitis, chemical burn is one of the most time-critically ocular emergencies that have been associated with various ocular and systemic conditions [1]. Retinal detachment is a rare condition in fertility patients. Several pharmacologic agents are available to induce or augment ovulation, but they have varying degrees of success. These medications include: clomiphene citrate (a selective estrogen receptor modulator), aromatase inhibitors, urinary and recombinant gonadotropins, gonadotropin-releasing hormone (GnRH) analogs and insulin-sensitizing agents. Clomiphene citrate (clomiphene citrate tablets USP) is the medication that is orally administered, it is non-steroidal ovulatory stimulant [2] and it was prescribed as an first-line treatment, because it’s many
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