Bilateral Renal Large B Cell Lymphoma in a Dog: A Case Report and Review of the Literature.

Emmanouela P Apostolopoulou,Katerina K Adamama-Moraitou,Georgia D Brellou,Paraskevi L Papadopoulou,Dimitra Pardali,Theofilos Poutahidis,Ioannis Vlemmas

doi:10.3390/vetsci8110258

Emmanouela P Apostolopoulou, Katerina K Adamama-Moraitou + Show 5 more

Open Access

https://doi.org/10.3390/vetsci8110258

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Abstract

Canine lymphoma is a commonly reported neoplasia and, in most dogs, arises from lymph nodes before spreading to other organs. Renal lymphoma rarely occurs, and kidneys usually are a secondary site of origin. Primary renal lymphoma is infrequently described in the veterinary literature. In this study, we present a rare case of primary renal lymphoma in a dog and a review of similar cases. A 3-year-old male dog was admitted due to anorexia, weakness and vomiting. Clinical examination revealed bilaterally enlarged kidneys. Imaging demonstrated the presence of multiple renal masses. Cytology of abdominal fluid and kidneys led to the diagnosis of large cell lymphoma. Histopathology and immunohistochemistry on tissue samples taken from the kidneys confirmed the cytological diagnosis of lymphoma and categorized it as primary bilateral renal large B-cell lymphoma (LBCL).

Highlights

Lymphoma accounts for approximately 80% of all canine hematopoietic tumors [1,2]
The most common type is diffuse large B-cell lymphoma with lymph nodes being the primary site of origin
2 and 9 years old, while in a 9-year-old dog unilateral involvement was seen. The objective of this case report was to present for the first time the clinical evaluation and imaging findings, as well as cytological and pathological features of a primary bilateral renal B-cell lymphoma case in a dog

Summary

Introduction

Lymphoma accounts for approximately 80% of all canine hematopoietic tumors [1,2]. The most common type is diffuse large B-cell lymphoma with lymph nodes being the primary site of origin. 16 cases of presumed primary renal lymphoma have been reported in dogs 2–9 years of age (Table 1) [1,12,13,14,15,16,17,18,19,20,21,22,23,24,25]. Among the 16 cases of canine renal lymphoma reported, nine of them were males, five were females and for two cases data was not available. 2 and 9 years old, while in a 9-year-old dog unilateral involvement was seen The objective of this case report was to present for the first time the clinical evaluation and imaging findings, as well as cytological and pathological features of a primary bilateral renal B-cell lymphoma case in a dog

Case Presentation

Findings

Discussion

Conclusions