Abstract

PurposeTo report a case of bilateral peripheral ulcerative keratitis (PUK) in a patient with underlying Sézary syndrome. ObservationsA 58-year-old male presented with bilateral corneal ulceration with stromal thinning and was diagnosed with PUK. He was actively being treated for Sézary syndrome, a cutaneous T-cell lymphoma. He had no lagophthalmos or other adnexal abnormalities that would lead to ocular surface breakdown. A systemic autoimmune and infectious workup for PUK was unremarkable. His keratitis resolved after treatment with oral prednisone. Conclusions and importanceWe describe a previously undocumented association of PUK with Sézary syndrome in a patient without adnexal disease.

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