Abstract

Abstract Background: An endometrial stromal tumor is a histopathologic entity characterized by a monomorphus population of blunt, spindle-to-oblong–shaped cells with scant cytoplasm in an abundant reticulin framework. This entity was first described in 1908, and was well-characterized by Norris and Taylor in 1966. It is classified as: (1) a benign stromal nodule; (2) a low-grade endometrial stromal sarcoma; or (3) an undifferentiated endometrial sarcoma. Endometrial stromal sarcomas usually arise from the uterine corpus. The most common extrauterine site is the ovary. Case: A 50-year-old female presented clinically with an abdominal lump. Radiologic findings were inconclusive and suggestive of a bilateral ovarian mass. Microscopic examination revealed a circumscribed tumor composed of uniform cells, having scanty cytoplasm, and having uniform nuclei showing nest and sex-cord differentiation that was seen blending with intervening stromal cells. Results: Immunoreactivity of tumor cells for cluster of diffe...

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