Bilateral Kimura’s disease of the both elbows: positron emission tomography/computed tomography findings—a case report

Abstract

Kimura’s disease is a rare idiopathic chronic lymphoproliferative disorder of unknown origin that occurs mainly in young Asian male patients [1]. The disease is characterized histopathologically by eosinophilic lymphofolliculoid granuloma with lymphoid hyperplasia and remarkable infiltration of the adjacent structures [2]. It mainly involves the head and neck, especially the parotid and submandibular regions [1]. Peripheral involvement is rare. Many articles have reported the imaging and histopathologic features of Kimura’s disease occurring at various sites, and the majority of these have described Kimura’s disease of the head and neck regions. To the best of our knowledge, however, there has only been two radiologic reports of Kimura’s disease involving the elbow bilaterally, which focused on magnetic resonance imaging (MRI) features [3] and high-resolution ultrasonography (US) [4]. Imaging findings of computed tomography (CT) scan or MRI have been discussed frequently, but images of fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) have not been reported in the literature before. We report a rare manifestation of Kimura’s disease, bilateral and multiple lymphadenopathy, in a young Asian woman. The imaging finding with FFDG PET/CT and MRI, clinical findings, and histopathologic features are described in detail. Case report