Bilateral keratoglobus in Down's syndrome

Abstract

Keratoglobus is a rare noninflammatory corneal thinning disorder categorized by progressive diminution of vision resulting from irregular corneal topography and increased corneal fragility due to extreme thinning. It is associated with blue sclera, hyperextensibility of the joints, or auditory problems. Down's syndrome is usually not associated with much visual disturbance. We report an unusual incidence of an adult male with Down's syndrome presenting with bilateral keratoglobus.