Abstract
Aim: To report a case of bilateral full-thickness macular hole formation after a single dose of conbercept injection.
 Method: A 46-year-old high myopic female developed full-thickness macular hole in both eyes at 7 and 19 days after intravitreal injection of conbercept. The myopic foveoschisis was misdiagnosed as macular edema. The macular holes in both eyes were repaired surgically.
 Results: The macular holes in both eyes were repaired successfully by surgery.
 Conclusion: The full-thickness macular hole formation could occur after anti-VEGF treatment. The possible reasons for this case might be traction caused by anti-VEGF agent or progression of myopic foveoschisis and PVD.
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