Bilateral acute anterior uveitis associated with MiraLAX bowel prep

Abstract

Drug-induced uveitis is vision-threatening and has been associated with various bioactive molecules. Here, we discuss a potential association between a polyethylene glycol 3350-based osmotic laxative, also known as MiraLAX, and bilateral anterior uveitis. We present a case of a 52-year-old gentleman with no significant medical history and a past ocular history of dry eye syndrome, who developed an anaphylactic reaction and acute but mild bilateral anterior uveitis after recent MiraLAX bowel preparation for a screening colonoscopy. Screening for medical problems was otherwise unremarkable. The patient responded well to topical steroids. We aim to raise awareness of the potential association between MiraLAX and uveitis to prevent vision loss.