Abstract

Bilastine, a non-sedating and long-acting second-generation antihistamine, is indicated for the symptomatic treatment of seasonal or perennial allergic rhinoconjunctivitis and urticaria in >90 countries worldwide. It has a favourable pharmacological profile, with a rapid onset of action and sustained efficacy over the 24-h dosing interval period, as well as a lack of CNS and cardiotoxic effects and clinically relevant drug interactions. In clinical trials, the efficacy of bilastine in treating rhinoconjunctivitis and urticaria was greater than that with placebo and generally similar to that of other second-generation antihistamines, and the overall tolerability profile of bilastine was similar to that of placebo.

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