Bijadushti Janya Asthi Dhatu Kshaya with Special Reference to Progressive Pseudo-Rheumatoid Arthropathy (Dysplasia) of Childhood – A Case Report

Abstract

Progressive pseudo-rheumatoid arthropathy dysplasia of childhood PPAC PPD is a genetic disorder characterized by poly articular non-inflammatory arthropathy due to impaired articular cartilage formation and maintenance caused by mutation in WISP3 WNT1-inducible signalling pathway protein 3 gene. Osteoarthritis joint space reduction and contracture formation results in severe handicap and incapacitation. Although few preventive measures are described to avert genetic disorders Ayurveda generally considers genetic disorders incurable. Hence palliative care becomes very important in managing such conditionsA North Indian 11.5 years old male child with Bijadushti Janya Vyadhi genetic disorder diagnosed as Progressive pseudo-rheumatoid arthropathy dysplasia of childhood PPAC PPD approached for pain and swelling of multiple joints gait and postural problems. Bijadushti was responsible for Asthi Dhatu Kshyaya diminution of bone tissue Sandhi Shotha joint swelling Sandhi Sankoch contractures Karma Hani loss of action and complications like lameness kyphosis and short stature in this case.He was managed with Ayurvedic treatment and Yoga and showed encouraging improvements in a short period. The treatment plan included Deepana-Pachana improving the digestion and metabolism Abhyanga therapeutic massage Swedana sudation and Basti therapeutic enema along with Asthidhatu Vardhana Chikitsa measures to supplement bone tissue Rasayana rejuvenation and range of motion ROM exercises in the form of Sukshma Vyayama gentle joint movements synchronized with breathing. If the etiopathogenesis of incurable genetic disorders is understood in the light of Ayurvedic tenets and palliative treatment is planned accordingly the patientrsquos life can be improved by providing symptomatic relief.