Abstract
AbstractAn efficient enantioselective Friedel–Crafts alkylation reaction of electron‐rich β‐naphthol with in situ generated ortho‐quinone methides catalyzed by chiral bifunctional amine‐squaramide catalysts has been developed. The chiral triarylmethane derivatives were obtained in good to high yields (up to 97% yield) with high enantioselectivities (up to 97% ee) for most substrates under mild conditions. This study also revealed that the oil‐water biphase could significantly improve the efficiency of this catalytic system.magnified image
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have