Abstract

AbstractThe intramolecular cyclization of the ambident anion 5 derived from condensation of N, O‐ditosylhydroxy‐L‐proline acid chloride with dimethyl malonate anion was studied under a variety of reaction conditions. Cyclization occurred solely by O‐alkylation to give 2‐oxa‐5‐azabicyclo[2.2.1 ]heptanes. The NMR speetra of the hicyclo compounds are diseussed.

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