Abstract
Objectives: The development of most pathologies in Marfan syndrome (MFS) is age dependent and thus not helpful for prediction of clinical outcome. Bicuspid aortic valve (BAV) is the most common congenital heart disease (2%). It is correlated with MFS and prevalence is up to 4.7% in adult patients with MFS. Nevertheless data in childhood about appearance and relevance for severity of phenotype is missing. Subsequently it may be a predictor for later onset of pathologies and helpful to determine individual patient care. We hereby evaluated correlation of appearance of BAV with other cardiovascular and systemic pathologies of MFS in childhood.
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