Abstract
This work represents active DNA concentration on piezoresistive microcantilever using biased AC electroosmosis. Two different sizes of DNA molecules, -phage DNA (48.5 kbp) and single-strand DNA of 20 nucleotides are concentrated on separate piezoresistive microcantilever sen- sor for detection. Before concentration, mixing of DNA molecules is performed using the same device for efficient concentration. During concentration of DNA molecules, biased and unbiased AC elec- troosmosis are needed to concentrate single-strand DNA and -phage DNA, respectively. Moreover, dielectrophoresis is induced by biased AC electroosmosis that can generate attractive force to trans- port negatively charged single-strand DNA. This paper represents a device configuration to integrate biased and unbiased AC electroosmosis and dielectrophoresis with piezoresistive microcantilever sen- sors for the detection of -phage DNA and single-strand DNA.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
